Wales' 93-cap full-back Liam Williams missed training on Friday in Rome as he struggles with a knee injury prior to Saturday's SIx Nations game against Italy.

Warren Gatland says that “everyone is aware of the situation” as Wales face a critical Guinness Six Nations clash against Italy in Rome. Wales are on the ropes, reeling from a record 13 successive Test match defeats and a 43-0 drubbing by France in their tournament opener.

Here are our Italy v Wales predictions in what has been billed as a Six Nations Wooden Spoon decider in Rome with the visitors having lost 13 games in a row

A win over Warren Gatland’s charges, who have lost their last 13 Test matches in a row, would see Italy claim just their second back-to-back home win in the Championship history

Wales travel to Italy on Saturday desperate to put last weekend’s thrashing by France behind them and finally get their Six Nations campaign up and running (2:15pm, ITV1). Warren Gatland’s side were beaten 43-0 in Paris on Friday, a record defeat for Wales in France, surpassing the 1991 36-3 loss.

WARREN GATLAND HAS dismissed the notion Wales are facing their biggest game for two decades against Italy on Saturday. Former Wales outside-half Dan Biggar described the Guinness Six Nations clash in Rome as Welsh rugby’s biggest game for the “last 15-20 years” after an opening 43-0 thrashing to France left Gatland’s side surveying a record-breaking 13th consecutive defeat.